Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30869745 | 0.89 | PDE10A (0.45) | PDE10AEGFRCD274MAP4K4ERBB2 | |
| SCHEMBL30869456 | 0.78 | EGFR (0.53) | EGFRMAP4K4ERBB2MAPK9CSNK1D | |
| SCHEMBL30869758 | 0.77 | KDM1A (0.47) | PDE10AEGFRCD274MAP4K4ERBB2 | |
| SCHEMBL30869841 | 0.77 | PDE10A (0.37) | PDE10ACD274MAP4K4MAPK9CSNK1D | |
| SCHEMBL30869734 | 0.73 | EGFR (0.55) | EGFRMAP4K4ERBB2MAPK9CSNK1D | |
| SCHEMBL30869573 | 0.73 | EGFR (0.53) | EGFRMAP4K4ERBB2MAPK9CSNK1D | |
| SCHEMBL30869570 | 0.72 | EGFR (0.52) | EGFRMAP4K4ERBB2MAPK9CSNK1D | |
| SCHEMBL30869552 | 0.72 | EGFR (0.52) | EGFRMAP4K4ERBB2MAPK9CSNK1D | |
| SCHEMBL30869414 | 0.72 | EGFR (0.50) | EGFRMAP4K4ERBB2MAPK9CSNK1D | |
| SCHEMBL30869877 | 0.72 | PIK3CD (0.48) | CSNK1DPIK3CATNIKTGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054661-A2 | DYNAMIN ACTIVATORS | WALDEN BIOSCIENCES (US) | 2024-03-14 | — | — | WO | disclosed |