Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346611 | 0.91 | PDE2A (0.33) | PDE2AHCRTR1HCRTR2 | |
| SCHEMBL30719552 | 0.83 | TRPV4 (0.39) | PDE2A | |
| SCHEMBL30719563 | 0.83 | TRPV4 (0.39) | PDE2A | |
| SCHEMBL27346590 | 0.83 | TRPV4 (0.39) | PDE2A | |
| SCHEMBL27346597 | 0.80 | KCNH2 (0.30) | — | |
| SCHEMBL27346552 | 0.75 | NR1H2 (0.38) | — | |
| SCHEMBL26065201 | 0.75 | KMT2A (0.38) | — | |
| SCHEMBL27346630 | 0.74 | — | — | |
| SCHEMBL30719527 | 0.73 | TRPV4 (0.40) | PDE2A | |
| SCHEMBL27346613 | 0.73 | TRPV4 (0.40) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |