Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710823 | 0.90 | DRD2 (0.53) | OPRK1OPRD1OPRM1DRD2DRD1 | |
| SCHEMBL20725551 | 0.88 | ANPEP (0.46) | HTR2ATAAR1ANPEPERAP1ERAP2 | |
| SCHEMBL499451 | 0.85 | HIF1A (0.51) | OPRK1OPRD1OPRM1KYNUADRB1 | |
| SCHEMBL7871790 | 0.85 | HIF1A (0.51) | OPRK1OPRD1OPRM1KYNUADRB1 | |
| SCHEMBL4748924 | 0.83 | KYNU (0.47) | KYNUADRB1MIFHTR2AADRA1A | |
| SCHEMBL5924988 | 0.82 | ANPEP (0.50) | HTR2ATAAR1ANPEPERAP1ERAP2 | |
| SCHEMBL855071 | 0.82 | ANPEP (0.50) | HTR2ATAAR1ANPEPERAP1ERAP2 | |
| SCHEMBL8067078 | 0.82 | ANPEP (0.50) | HTR2ATAAR1ANPEPERAP1ERAP2 | |
| SCHEMBL20725527 | 0.81 | LOXL2 (0.48) | HTR2ATAAR1ANPEPERAP1ERAP2 | |
| SCHEMBL27549431 | 0.81 | ADRA1A (0.51) | OPRK1OPRM1ADRB1HTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045780-A | The preparation of new sulfonamide derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-03 | — | — | CN | disclosed |