Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562635 | 0.85 | ALDH1A1 (0.44) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL18034526 | 0.85 | ALDH1A1 (0.49) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL6629323 | 0.83 | HRH4 (0.54) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL27348057 | 0.80 | NGFR (0.43) | ALOX15KDM4EHPGDSMN1; SMN2HRH4 | |
| SCHEMBL1243869 | 0.77 | CDK1 (0.48) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL4100907 | 0.77 | ALDH1A1 (0.43) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL1242423 | 0.77 | PYGL (0.44) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL1244756 | 0.77 | ALOX15 (0.56) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL6627447 | 0.74 | KDM4E (0.46) | ALOX15CDK1CCNB1ALDH1A1KDM4E | |
| SCHEMBL1244037 | 0.74 | HRH4 (0.52) | ALOX15CDK1CCNB1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |