Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242423 | 0.89 | PYGL (0.44) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3562635 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL18034526 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6629323 | 0.83 | HRH4 (0.54) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL31229783 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL1242296 | 0.78 | RAB9A (0.43) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL27348017 | 0.77 | ALOX15 (0.47) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1244590 | 0.77 | RAB9A (0.51) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL20745602 | 0.74 | RAB9A (0.46) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6627447 | 0.74 | KDM4E (0.46) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | ALDH1A1 2718/4885KDM4E 583/4885HPGD 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.