SCHEMBL273489

SCHEMBL273489

Cc1ccccc1[SiH](O)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 3/20 0.33
ESR1 P03372 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
TRPA1 O75762 2/20 0.30
ATM Q13315 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271788 0.75 TSHR (0.47) ACHETSHRALDH1A1CA1CA2
SCHEMBL9356901 0.74 TSHR (0.41) ACHETSHRALDH1A1ESR1CA1
SCHEMBL27943186 0.73 TSHR (0.45) ACHETSHRALDH1A1CA1CA2
SCHEMBL272693 0.72 TSHR (0.35) ACHETSHRALDH1A1MAOAMAOB
SCHEMBL15641904 0.71 TSHR (0.43) ACHETSHRALDH1A1CA1CA2
SCHEMBL1557214 0.69 TSHR (0.53) ACHETSHRALDH1A1ESR1CA1
SCHEMBL7183345 0.69 LMNA (0.34) TSHRALDH1A1CYP3A4TDP1TRPA1
SCHEMBL16393929 0.68 ACHE (0.39) ACHETSHRALDH1A1ESR1CA1
SCHEMBL13720383 0.68 ACHE (0.39) ACHETSHRALDH1A1CA1CA2
SCHEMBL29776872 0.67 TSHR (0.50) ACHETSHRALDH1A1ESR1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120153318-A Photosensitive resin composition, method for producing cured relief pattern using same, and method for producing polyimide film 旭化成株式会社 2025-06-13 CN disclosed
CN-114207038-B Resin composition, method for producing cured product, pattern cured product, interlayer insulating film, covercoat, surface protective film, and electronic component 艾曲迪微系统股份有限公司 2024-03-22 CN disclosed
US-11592744-B2 Positive-type photosensitive resin composition HD MICROSYSTEMS, LTD. (JP) 2023-02-28 US disclosed
CN-110088680-B Double-layer photosensitive layer roll 旭化成株式会社 2022-12-30 CN disclosed
CN-112334833-A Negative photosensitive resin composition, polyimide using same, and method for producing cured relief pattern 旭化成株式会社 2021-02-05 CN disclosed
EP-3413132-B1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION HD MICROSYSTEMS LTD (JP) 2020-12-16 EP disclosed
US-20190049842-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION HD MICROSYSTEMS, LTD. (JP) 2019-02-14 US disclosed
EP-3413132-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION Hitachi Chemical DuPont Microsystems, Ltd. (JP) 2018-12-12 EP disclosed
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-8133550-B2 Good breaking elongation characteristics, achievable high sensitivity and high film remaining rate, little in pattern size fluctuation at the heating time after lithographic process, capable of stable pattern formation; manufacturing a semiconductor device FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE CD79B, BRIX1, SMARCB1 ACHE 4165/4885TSHR 3177/4885ALDH1A1 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.