Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068444 | 0.77 | FKBP1A (0.82) | FKBP1AALDH1A1TSHRPOLBSIGMAR1 | |
| SCHEMBL1953978 | 0.75 | FKBP1A (0.80) | FKBP1APOLBSIGMAR1NPSR1FAAH | |
| SCHEMBL9556702 | 0.74 | FKBP1A (0.78) | FKBP1APOLBNPSR1FAAHMAPT | |
| SCHEMBL15312924 | 0.73 | ALOX5 (0.71) | ALOX5KMT2AMEN1MAPTRAB9A | |
| SCHEMBL17117357 | 0.73 | NAMPT (0.66) | FKBP1AKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL8327592 | 0.73 | FKBP1A (1.00) | FKBP1AKMT2AALDH1A1TSHRPOLB | |
| SCHEMBL8602590 | 0.72 | HRH3 (0.58) | FKBP1AKMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL17117403 | 0.72 | NAMPT (0.67) | FKBP1AKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL6629759 | 0.71 | FKBP1A (0.52) | FKBP1AMLYCDKMT2AALDH1A1TSHR | |
| SCHEMBL16909085 | 0.71 | POLB (0.52) | FKBP1AALOX5KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027271-C | Preparation method of n-statinib and n-cyclostatini polypeptide | PFICER CO LTD (US) | 1995-01-04 | — | — | CN | disclosed |
| CN-87101499-A | Preparation method of n-statinib and n-cyclostatini polypeptide | — | 1988-05-11 | — | — | CN | disclosed |