Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602590 | 0.81 | HRH3 (0.58) | FKBP1AALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL7659276 | 0.76 | KMT2A (0.60) | FKBP1AALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL8944585 | 0.74 | LMNA (0.42) | FKBP1AALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL7405546 | 0.73 | NPC1 (0.48) | ALDH1A1KMT2AMEN1NPSR1TSHR | |
| SCHEMBL20236319 | 0.72 | TPSAB1 (0.50) | FKBP1AALDH1A1KMT2AMEN1NPSR1 | |
| Hydrochloric Acid SCHEMBL11685888 | 0.71 | NPC1 (0.47) | ALDH1A1KMT2AMEN1NPSR1TSHR | |
| SCHEMBL27353136 | 0.71 | FKBP1A (0.57) | FKBP1AALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL20236677 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15855778 | 0.71 | MMP8 (0.49) | FKBP1AALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL1516144 | 0.71 | MAPT (0.82) | FKBP1AALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317459-B1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-04-07 | — | — | EP | claimed |