Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325421 | 0.86 | CHRM2 (0.44) | — | |
| SCHEMBL8948208 | 0.86 | SIGMAR1 (0.44) | — | |
| SCHEMBL7756742 | 0.83 | CHRM2 (0.48) | SCN8A | |
| SCHEMBL8948251 | 0.77 | CNR1 (0.33) | — | |
| SCHEMBL7760542 | 0.77 | SCN8A (0.41) | SCN8ATMEM97KCNH2MC4RPHGDH | |
| Hydrochloric Acid SCHEMBL8871371 | 0.74 | L3MBTL1 (0.40) | KCNH2 | |
| SCHEMBL8110040 | 0.74 | ALDH1A1 (0.39) | HRH3 | |
| SCHEMBL8109679 | 0.73 | MAPT (0.41) | TMEM97ADRB2 | |
| SCHEMBL9684037 | 0.73 | S1PR1 (0.38) | — | |
| SCHEMBL7760492 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050601-C | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-03-22 | — | — | CN | disclosed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | disclosed |