SCHEMBL9684037

SCHEMBL9684037

CCCCCc1ccc2c(c1)[S+]([O-])CN2C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.38
GPR3 P46089 1/20 0.38
THRA P10827 2/20 0.37
THRB P10828 2/20 0.37
SPHK1 Q9NYA1 2/20 0.37
SIGMAR1 Q99720 1/20 0.37
ESR1 P03372 2/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37
TACR2 P21452 2/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
HTR2C P28335 2/20 0.37
HTR2A P28223 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
SHBG P04278 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685609 0.95 DRD2 (0.39) S1PR1THRATHRBSIGMAR1HTR2C
SCHEMBL9685749 0.89 CNR1 (0.36) SIGMAR1ADRA2AHTR2CHTR2AADRA2B
SCHEMBL9684946 0.87 BCHE (0.37) S1PR1ACHECA2PRKCGPRKCB
Hydrochloric Acid SCHEMBL8870829 0.86 TLR8 (0.35) SIGMAR1HTR2A
SCHEMBL7760492 0.85
Hydrochloric Acid SCHEMBL8871371 0.83 L3MBTL1 (0.40) SIGMAR1SLC6A2SLC6A4SLC6A3HTR2C
SCHEMBL9684023 0.83 KDM4E (0.35) SLC6A2SLC6A4SLC6A3KDM4E
SCHEMBL8114240 0.82 KDM4E (0.37) ADRA2ASLC6A2SLC6A3KDM4EALDH1A1
SCHEMBL7761425 0.82 GRIA2 (0.31)
SCHEMBL9437722 0.82 SIGMAR1 (0.36) THRATHRBSIGMAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084469-A Analgesics ADIR ET COMPAGNIE (FR) 1992-01-28 US disclosed