Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012347 | 0.82 | ATP4A (0.33) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL27354244 | 0.80 | MC4R (0.35) | ADRA2AADRA2BADRA2CNPC1RAB9A | |
| SCHEMBL9012162 | 0.78 | TAAR1 (0.35) | TAAR1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL27342985 | 0.78 | ADRA2A (0.40) | TAAR1ADRA2ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9012337 | 0.78 | TAAR1 (0.35) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL6527231 | 0.78 | TAAR1 (0.47) | TAAR1ADRA2ASMN1; SMN2HSD17B10MTOR | |
| SCHEMBL27270255 | 0.77 | ADRA2A (0.31) | ADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL27357187 | 0.77 | TAAR1 (0.46) | TAAR1ADRA2AADRA2CPOLBNPC1 | |
| SCHEMBL9011902 | 0.76 | AR (0.36) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL8517908 | 0.76 | ADRA2A (0.33) | TAAR1ADRA2AADRA2BADRA2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058594-A | Imidazo [4,5-C] pyridines osteoporosis agent | AMERICAN HOME PROD (US) | 1992-02-12 | — | — | CN | claimed |
| CN-1058594-A | Imidazo [4,5-C] pyridines osteoporosis agent | AMERICAN HOME PROD (US) | 1992-02-12 | — | — | CN | disclosed |