Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364674 | 0.83 | TAAR1 (0.45) | TAAR1CYP2D6TSHRMTORADK | |
| SCHEMBL27525402 | 0.83 | CYP1A2 (0.39) | TAAR1CYP2D6TSHRHSD17B10 | |
| SCHEMBL27357182 | 0.82 | CDK8 (0.37) | TAAR1SMN1; SMN2 | |
| SCHEMBL4935105 | 0.80 | MAPT (0.40) | TAAR1CYP2D6SMN1; SMN2 | |
| SCHEMBL27357185 | 0.80 | ADRA2A (0.36) | LMNASMN1; SMN2ADRA1AADRA2AADRA1D | |
| SCHEMBL27342986 | 0.80 | LMNA (0.37) | TAAR1LMNASMN1; SMN2ADRA1AADRA2A | |
| SCHEMBL9012315 | 0.79 | BACE1 (0.42) | TAAR1TSHRHSD17B10 | |
| SCHEMBL27341816 | 0.78 | FGFR1 (0.43) | TAAR1LMNASMN1; SMN2 | |
| SCHEMBL27343501 | 0.78 | ACP3 (0.40) | TAAR1HTR2B | |
| SCHEMBL9012347 | 0.78 | ATP4A (0.33) | TAAR1MTORADKNISCHADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058594-A | Imidazo [4,5-C] pyridines osteoporosis agent | AMERICAN HOME PROD (US) | 1992-02-12 | — | — | CN | claimed |
| US-6906078-B2 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | PHARMACIA CORPORATION (US) | 2005-06-14 | — | — | US | disclosed |
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | MOORMAN ALAN E (US) | 2001-11-29 | — | — | US | disclosed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |
| CN-1020902-C | IMIDAZOLE DERIVATIVE AND PROCESSES FOR PREPARING SAME | TANAHBE SEIYAKU CO LTD (JP) | 1993-05-26 | — | — | CN | disclosed |
| CN-1058594-A | Imidazo [4,5-C] pyridines osteoporosis agent | AMERICAN HOME PROD (US) | 1992-02-12 | — | — | CN | disclosed |
| CN-87108111-A | Novel imidazole derivative and preparation method thereof | — | 1988-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | ATP4A, ATP1A1, ATP1A4 | TAAR1 1705/4885CYP2D6 707/4885TSHR 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.