Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1348352 | 0.79 | MAPT (0.42) | KMT2AMAPK1HIF1AFBP1NPC1 | |
| Nitric Acid SCHEMBL9874831 | 0.72 | MEN1 (0.44) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL1016971 | 0.71 | KMT2A (0.71) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL4297794 | 0.71 | MEN1 (0.71) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL26402 | 0.71 | MEN1 (1.00) | KMT2AMEN1TSHRMAPK1HIF1A | |
| 1,4-Dichlorobenzene SCHEMBL4397293 | 0.71 | TSHR (0.61) | KMT2AMEN1TSHRMAPK1HIF1A | |
| 1,4-Dichlorobenzene SCHEMBL29002852 | 0.70 | FBP1 (0.52) | KMT2AMEN1TSHRMAPK1FBP1 | |
| 1,4-Dichlorobenzene SCHEMBL28182719 | 0.70 | FBP1 (0.50) | KMT2AMEN1TSHRMAPK1FBP1 | |
| SCHEMBL31649209 | 0.69 | ALDH1A1 (0.52) | KMT2AMEN1TSHRMAPK1POLB | |
| SCHEMBL7266587 | 0.69 | ALDH1A1 (0.52) | KMT2AMEN1TSHRMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040747-C | N-substituting group-4-substituted benzyl-5-alkyl-5-substituted benzyl-pyrrolidone-2, and its intermediate, its synthetic method and its appliance | KUNMING PLANT INST CHINESE ACA (CN) | 1998-11-18 | — | — | CN | disclosed |
| CN-1120036-A | N-substituting group-4-substituted benzyl-5-alkyl-5-substituted benzyl-pyrrolidone-2, and its intermediate, its synthetic method and its appliance | KUNMING PLANT INST CHINESE ACA (CN) | 1996-04-10 | — | — | CN | disclosed |