Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384260 | 0.81 | LMNA (0.45) | GAATHRBATML3MBTL1NOS3 | |
| SCHEMBL19833478 | 0.79 | PIK3CD (0.42) | — | |
| SCHEMBL13107602 | 0.79 | PRMT5 (0.46) | ALDH1A1LIPCLIPGPDE4B | |
| SCHEMBL27357675 | 0.79 | GAA (0.43) | GAATHRBATML3MBTL1NOS3 | |
| SCHEMBL9051469 | 0.77 | SMN1; SMN2 (0.43) | GAAL3MBTL1GBA2LMNAPOLB | |
| SCHEMBL24348077 | 0.77 | GAA (0.53) | GAATHRBATML3MBTL1NOS3 | |
| SCHEMBL26465066 | 0.77 | GAA (0.46) | GAATHRBATML3MBTL1NOS3 | |
| SCHEMBL24943351 | 0.75 | GNAI3 (0.56) | L3MBTL1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL30744688 | 0.74 | ALDH1A1 (0.47) | GAATHRBATML3MBTL1NOS3 | |
| SCHEMBL24673636 | 0.74 | HRH2 (0.41) | ALDH1A1LMNASMN1; SMN2GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050742-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS G12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |