Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL45788 | 0.96 | TSHR (0.31) | — | |
| Water SCHEMBL6246044 | 0.92 | — | — | |
| Hydrogen Sulfide SCHEMBL28090943 | 0.92 | TSHR (0.33) | — | |
| SCHEMBL197824 | 0.92 | TSHR (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL28002000 | 0.89 | — | — | |
| Water SCHEMBL11621604 | 0.89 | — | — | |
| Lithium Ion SCHEMBL2504315 | 0.88 | TSHR (0.31) | — | |
| SCHEMBL596385 | 0.88 | TSHR (0.31) | — | |
| Iodide SCHEMBL2796494 | 0.88 | TSHR (0.31) | — | |
| SCHEMBL5327324 | 0.88 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041518-C | Process for preparing substituted aromatic amines | MONSANTO CO (US) | 1999-01-06 | — | — | CN | disclosed |
| CN-1098403-A | The method of the aromatic amine that preparation replaces | MONSANTO CO (US) | 1995-02-08 | — | — | CN | disclosed |