SCHEMBL2736012

SCHEMBL2736012

COCNc1nc(-c2ccccc2)nc(N(COC)C(C)=O)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.39
ALOX15 P16050 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 4/20 0.37
TP53 P04637 3/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 2/20 0.36
RECQL P46063 1/20 0.36
TPH1 P17752 2/20 0.36
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
F2 P00734 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
IDH1 O75874 1/20 0.35
IMPDH2 P12268 2/20 0.35
PRNP P04156 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2612607 0.83 IDH1 (0.40) GAAALOX15LMNATSHRMAPK1
SCHEMBL2736011 0.83 ALDH1A1 (0.41) GAAALOX15LMNATSHRMAPK1
SCHEMBL2736013 0.81 ALDH1A1 (0.39) GAAALOX15LMNATSHRMAPK1
SCHEMBL13140693 0.81 IDH1 (0.36) GAAALOX15LMNATSHRMAPK1
SCHEMBL14817365 0.79 KMT2A (0.36) GAAALOX15LMNATSHRMAPK1
SCHEMBL18053211 0.79 ALDH1A1 (0.35) GAAALOX15LMNATSHRMAPK1
SCHEMBL13140695 0.78 IDH1 (0.53) ALDH1A1KMT2ANPSR1IDH1IMPDH2
SCHEMBL14123279 0.78 LMNA (0.55) GAAALOX15LMNATSHRMAPK1
SCHEMBL16351816 0.77 PRUNE1 (0.39) GAAALOX15LMNATSHRMAPK1
SCHEMBL16361834 0.77 KMT2A (0.38) GAAALOX15LMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679709-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and film forming coating solution FUJI XEROX CO., LTD. (JP) 2014-03-25 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8090298-B2 Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-03 US disclosed
US-20100247148-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20100104316-A1 ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-04-29 US disclosed
US-20090238602-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-09-24 US disclosed
US-20090004583-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND FILM FORMING COATING SOLUTION FUJI XEROX CO., LTD. (JP) 2009-01-01 US disclosed