SCHEMBL2736013

SCHEMBL2736013

CCCCOCNc1nc(-c2ccccc2)nc(N(COCCCC)C(C)=O)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 4/20 0.37
GAA P10253 3/20 0.37
LMNA P02545 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 2/20 0.37
GLA P06280 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ADORA3 P0DMS8 1/20 0.36
ADORA1 P30542 1/20 0.36
MAPK8 P45983 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13140700 0.86 POLB (0.39) ALDH1A1TSHRGAALMNAMEN1
SCHEMBL14817367 0.82 POLB (0.36) ALDH1A1KDM4ESMN1; SMN2TSHRGAA
SCHEMBL2736010 0.82 ALDH1A1 (0.39) ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL2736012 0.81 GAA (0.39) ALDH1A1KDM4ERAB9ASMN1; SMN2TSHR
SCHEMBL13936631 0.77 MEN1 (0.43) ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL724229 0.76 NPSR1 (0.57) ALDH1A1TSHRGAALMNAMEN1
SCHEMBL13133049 0.76 MEN1 (0.31) RAB9AMEN1KMT2ATDP1
SCHEMBL13133040 0.75 CNR2 (0.31) RAB9AMEN1KMT2ATDP1
SCHEMBL8640915 0.74 BCHE (0.41) ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL13241909 0.74 IDH1 (0.48) ALDH1A1KDM4ERAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679709-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and film forming coating solution FUJI XEROX CO., LTD. (JP) 2014-03-25 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8090298-B2 Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-03 US disclosed
US-20100247148-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20100104316-A1 ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-04-29 US disclosed
US-20090238602-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-09-24 US disclosed
US-20090004583-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND FILM FORMING COATING SOLUTION FUJI XEROX CO., LTD. (JP) 2009-01-01 US disclosed