SCHEMBL2736018

SCHEMBL2736018

CCCCOCN(COC)c1nc(NC(C)=O)nc(-c2cccc(C)c2)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
GAA P10253 2/20 0.36
MAPK1 P28482 2/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ADORA3 P0DMS8 3/20 0.35
ADORA1 P30542 3/20 0.35
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.33
MAPK14 Q16539 1/20 0.33
RORC P51449 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
DHPS P49366 1/20 0.33
MAPT P10636 4/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2736017 0.86 MEN1 (0.35) GAAPPARDPPARADHPSRAB9A
SCHEMBL14817379 0.85 IDH1 (0.33) LMNAGAATSHRDHPSRAB9A
SCHEMBL437593 0.82 RAB9A (0.35) LMNATSHRADORA3ADORA2ASMN1; SMN2
SCHEMBL18053222 0.80 KMT2A (0.34) LMNAGAATSHRRORCPPARD
SCHEMBL14817378 0.80 TP53 (0.33) LMNAGAATSHRSMN1; SMN2DHPS
SCHEMBL16362260 0.78 RAB9A (0.39) LMNATSHRADORA3ADORA2ASMN1; SMN2
SCHEMBL2760070 0.75 RAB9A (0.49) LMNAMAPK1TSHRSMN1; SMN2DHPS
SCHEMBL2736016 0.75 RAB9A (0.40) LMNAGAATSHRSMN1; SMN2DHPS
SCHEMBL2736010 0.75 ALDH1A1 (0.39) GAATSHRADORA3ADORA1SMN1; SMN2
SCHEMBL21414071 0.74 BCHE (0.38) MAPK1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679709-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and film forming coating solution FUJI XEROX CO., LTD. (JP) 2014-03-25 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8090298-B2 Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-03 US disclosed
US-20100247148-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20100104316-A1 ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-04-29 US disclosed
US-20090238602-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-09-24 US disclosed
US-20090004583-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND FILM FORMING COATING SOLUTION FUJI XEROX CO., LTD. (JP) 2009-01-01 US disclosed