SCHEMBL2736017

SCHEMBL2736017

CCCCOCN(COC)c1nc(-c2cccc(C)c2)nc(N(COC)C(C)=O)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 2/20 0.35
ALDH1A1 P00352 3/20 0.34
DHPS P49366 1/20 0.34
HPGD P15428 1/20 0.34
ATM Q13315 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
DHODH Q02127 1/20 0.33
CCNE2 O96020 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
PTPN11 Q06124 1/20 0.33
RAB9A P51151 2/20 0.33
HDAC1 Q13547 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33
HAVCR2 Q8TDQ0 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2736016 0.90 RAB9A (0.40) MEN1KMT2ATP53ALDH1A1DHPS
SCHEMBL2736010 0.87 ALDH1A1 (0.39) MEN1KMT2ATDP1TP53ALDH1A1
SCHEMBL437593 0.86 RAB9A (0.35) MEN1KMT2ATDP1TP53ALDH1A1
SCHEMBL2736018 0.86 LMNA (0.36) TP53DHPSHPGDPPARDPPARA
SCHEMBL14817378 0.84 TP53 (0.33) MEN1KMT2ATDP1TP53ALDH1A1
SCHEMBL16362260 0.82 RAB9A (0.39) MEN1KMT2ATDP1TP53ALDH1A1
SCHEMBL13233286 0.81 MEN1 (0.38) MEN1KMT2ATDP1ALDH1A1ATM
SCHEMBL14817379 0.80 IDH1 (0.33) TDP1TP53ALDH1A1DHPSHPGD
SCHEMBL2760070 0.80 RAB9A (0.49) MEN1KMT2ATDP1TP53ALDH1A1
SCHEMBL21414071 0.79 BCHE (0.38) MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679709-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and film forming coating solution FUJI XEROX CO., LTD. (JP) 2014-03-25 US disclosed
US-8655220-B2 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-02-18 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8090298-B2 Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-03 US disclosed
US-20100247148-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20100104316-A1 ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-04-29 US disclosed
US-20090238602-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-09-24 US disclosed
US-20090004583-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND FILM FORMING COATING SOLUTION FUJI XEROX CO., LTD. (JP) 2009-01-01 US disclosed