SCHEMBL2736016

SCHEMBL2736016

COCN(COC)c1nc(-c2cccc(C)c2)nc(N(COC)C(C)=O)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
TP53 P04637 4/20 0.38
HAVCR2 Q8TDQ0 1/20 0.37
ALDH1A1 P00352 5/20 0.37
HPGD P15428 3/20 0.37
DHPS P49366 1/20 0.37
ATM Q13315 1/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
LMNA P02545 3/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 5/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2736017 0.90 MEN1 (0.35) RAB9ATP53HAVCR2ALDH1A1HPGD
SCHEMBL2760070 0.89 RAB9A (0.49) RAB9ATP53ALDH1A1HPGDDHPS
SCHEMBL16351811 0.83 RAB9A (0.41) RAB9ATP53ALDH1A1HPGDDHPS
SCHEMBL18053220 0.83 RAB9A (0.41) RAB9ATP53ALDH1A1HPGDDHPS
SCHEMBL438949 0.83 RAB9A (0.43) RAB9ATP53ALDH1A1HPGDDHPS
SCHEMBL16362250 0.81 RAB9A (0.40) RAB9ATP53ALDH1A1HPGDDHPS
SCHEMBL14817377 0.80 RAB9A (0.39) RAB9ATP53ALDH1A1HPGDDHPS
SCHEMBL13936637 0.77 GAA (0.36) RAB9ATP53ALDH1A1TSHRSMN1; SMN2
SCHEMBL2736002 0.76 CRHR1 (0.33) ALDH1A1TSHRSMN1; SMN2HTT
SCHEMBL2736018 0.75 LMNA (0.36) RAB9ATP53HPGDDHPSTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8679709-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, and film forming coating solution FUJI XEROX CO., LTD. (JP) 2014-03-25 US disclosed
US-8655220-B2 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-02-18 US disclosed
US-8535861-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2013-09-17 US disclosed
US-8090298-B2 Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-03 US disclosed
US-20100247148-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20100104316-A1 ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-04-29 US disclosed
US-20090238602-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-09-24 US disclosed
US-20090004583-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND FILM FORMING COATING SOLUTION FUJI XEROX CO., LTD. (JP) 2009-01-01 US disclosed