Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362843 | 0.83 | CYP3A4 (0.38) | ALDH1A1TSHRHSD17B10CYP3A4SNCA | |
| SCHEMBL27348053 | 0.73 | LPO (0.42) | ALDH1A1CYP3A4ARG1MAPTMEN1 | |
| SCHEMBL5694138 | 0.72 | NPSR1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4SNCA | |
| SCHEMBL5803359 | 0.70 | SLC22A12 (0.45) | ALDH1A1TSHRHSD17B10CYP3A4SNCA | |
| SCHEMBL5694101 | 0.69 | AHCY (0.39) | ALDH1A1TSHRHSD17B10LMNAMAPK1 | |
| SCHEMBL5694096 | 0.69 | CDK1 (0.45) | — | |
| SCHEMBL5694260 | 0.69 | GSK3B (0.56) | ALDH1A1 | |
| SCHEMBL5694117 | 0.67 | SMN1; SMN2 (0.37) | ALDH1A1TSHRHSD17B10CYP3A4NPSR1 | |
| SCHEMBL7122663 | 0.67 | ALDH1A1 (0.35) | ALDH1A1TSHRHSD17B10CYP3A4NPSR1 | |
| SCHEMBL9791261 | 0.66 | ASAH1 (0.47) | ALDH1A1HSD17B10CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057091-C | Novelc arbapenem derivatives | MEIJI SEIKA CO (JP) | 2000-10-04 | — | — | CN | disclosed |
| CN-1148390-A | Novelc arbapenem derivatives | MEIJI SEIKA CO (JP) | 1997-04-23 | — | — | CN | disclosed |