Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | BRAF | P15056 | 3/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360679 | 0.92 | ROCK2 (0.37) | ELANEXIAPMLXBRAFMAPK1 | |
| SCHEMBL27360586 | 0.91 | DPP4 (0.40) | ELANEXIAPMLXABL1BRAF | |
| SCHEMBL27360684 | 0.87 | CYP3A4 (0.34) | ELANEXIAPMLXBRAFMAPK1 | |
| SCHEMBL27360583 | 0.86 | DPP4 (0.37) | ELANEXIAPMLXMAPK1KCNH2 | |
| SCHEMBL27360675 | 0.86 | ELANE (0.38) | ELANEXIAPMLXKCNH2CYP3A4 | |
| SCHEMBL27360670 | 0.85 | ELANE (0.36) | ELANEXIAPMLXMAPK1KCNH2 | |
| SCHEMBL27360584 | 0.85 | ELANE (0.35) | ELANEXIAPMLXMAPK1VHL | |
| SCHEMBL27360367 | 0.78 | XIAP (0.38) | PTGESPTGS2ELANEXIAPMLX | |
| SCHEMBL26847747 | 0.74 | VHL (0.51) | VHL | |
| SCHEMBL27360361 | 0.72 | MAPK1 (0.38) | ELANEXIAPMLXPREPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |