Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360587 | 0.91 | PTGES (0.35) | PREPFAPELANECCR5KCNH2 | |
| SCHEMBL27360679 | 0.90 | ROCK2 (0.37) | ELANECCR5KCNH2MAPK1BRAF | |
| SCHEMBL27360684 | 0.86 | CYP3A4 (0.34) | ELANEKCNH2MAPK1BRAFVHL | |
| SCHEMBL27360583 | 0.85 | DPP4 (0.37) | DPP4ELANEKCNH2MAPK1XIAP | |
| SCHEMBL27360675 | 0.84 | ELANE (0.38) | DPP4ELANEKCNH2XIAPMLX | |
| SCHEMBL27360584 | 0.84 | ELANE (0.35) | ELANEKCNH2MAPK1VHLXIAP | |
| SCHEMBL27360670 | 0.84 | ELANE (0.36) | ELANEKCNH2MAPK1XIAPMLX | |
| SCHEMBL26847747 | 0.73 | VHL (0.51) | VHL | |
| SCHEMBL27360088 | 0.71 | VHL (0.42) | DPP4VHL | |
| SCHEMBL30760141 | 0.71 | DPP4 (0.47) | DPP4VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |