Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 8/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360584 | 0.94 | ELANE (0.35) | TACR1ELANEXIAPMLXCYP3A4 | |
| SCHEMBL27360670 | 0.91 | ELANE (0.36) | TACR1ELANEXIAPMLXCYP3A4 | |
| SCHEMBL27360675 | 0.89 | ELANE (0.38) | DPP4ELANEXIAPMLXCYP3A4 | |
| SCHEMBL27360679 | 0.88 | ROCK2 (0.37) | ELANEXIAPMLXKCNH2MAPK1 | |
| SCHEMBL27360587 | 0.86 | PTGES (0.35) | ELANEXIAPMLXCYP3A4CYP2C9 | |
| SCHEMBL27360684 | 0.85 | CYP3A4 (0.34) | ELANEXIAPMLXCYP3A4CYP2C9 | |
| SCHEMBL27360586 | 0.85 | DPP4 (0.40) | DPP4ELANEXIAPMLXKCNH2 | |
| SCHEMBL26847747 | 0.76 | VHL (0.51) | — | |
| SCHEMBL24756884 | 0.75 | VHL (0.49) | — | |
| SCHEMBL27360081 | 0.74 | VHL (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |