Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 7/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389183 | 0.81 | NOTUM (0.33) | POLB | |
| SCHEMBL27640315 | 0.73 | TDP1 (0.40) | — | |
| SCHEMBL27640310 | 0.70 | HCAR1 (0.36) | — | |
| SCHEMBL27259672 | 0.66 | HTR3E (0.46) | — | |
| Hydrochloric Acid SCHEMBL9222016 | 0.63 | CHRNB2 (0.51) | CHRNB4CHRNA3CHRNB2CHRNA4POLB | |
| SCHEMBL27544106 | 0.58 | — | — | |
| SCHEMBL28253765 | 0.58 | — | — | |
| SCHEMBL29998481 | 0.58 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4POLB | |
| SCHEMBL10339123 | 0.58 | POLB (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4POLB | |
| SCHEMBL25327467 | 0.58 | ALDH1A1 (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067999-C | Anti-helicobacter heterocyclic derivatives of azolines | JANSSEN PHARMACEUTICA NV (BE) | 2001-07-04 | — | — | CN | disclosed |
| CN-1152310-A | Anti-helicobacter heterocyclic derivatives of azolines | JANSSEN PHARMACEUTICA NV (BE) | 1997-06-18 | — | — | CN | disclosed |