Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736334 | 0.86 | USP2 (0.38) | MAOBALOX5PTGS1PTGS2MAPT | |
| SCHEMBL27625548 | 0.86 | CYP1A2 (0.36) | MAOBKCNH2GPR183LMNA | |
| SCHEMBL27756903 | 0.82 | CYP1A2 (0.41) | HSD11B1KMT2AGPR183ALDH1A1LMNA | |
| SCHEMBL27736309 | 0.80 | PYGL (0.42) | PTGS2ALDH1A1 | |
| SCHEMBL27469722 | 0.79 | SLC6A2 (0.43) | HTR2CHTR2BHTR2AKCNH2PTGS1 | |
| SCHEMBL28779017 | 0.76 | CYP1A2 (0.42) | MAOBKMT2AALDH1A1LMNA | |
| SCHEMBL8487694 | 0.74 | SLC6A2 (0.41) | CYP11B1CYP11B2HTR2CHTR2BALDH1A1 | |
| SCHEMBL4321271 | 0.74 | CHRM1 (0.42) | HSD11B1MAOBKMT2AHTR2CHTR2B | |
| SCHEMBL4321273 | 0.74 | CHRM1 (0.42) | HSD11B1MAOBKMT2AHTR2CHTR2B | |
| SCHEMBL27587931 | 0.72 | MAPK1 (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282643-C | Intermediate for preparing compounds having serotonin-2 receptor antagonistic and alpha-1 blocking action and its preparing method | DAIICHI SUNTORY SEIYAKU CO LTD (JP) | 2006-11-01 | — | — | CN | disclosed |
| CN-1193014-C | Novol pyrrole sulphamide compound | DAICHI SUNTORY PHARMA CO LTD (JP) | 2005-03-16 | — | — | CN | disclosed |
| CN-1528746-A | Intermediate for preparing compounds having serotonin-2 receptor antagonistic and alpha-1 blocking action and its preparing method | ��һ��������ҩ��ʽ���� | 2004-09-15 | — | — | CN | disclosed |
| CN-1495163-A | Novol pyrrole sulphamide compound | ��һ��������ҩ��ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| CN-1148372-C | Has 5-hydroxytryptamine-2 receptor antagonistic effect and alpha1Azothiazines and pyrrolethiones with blocking actionAzepine compound | ��һ��������ҩ��ʽ���� | 2004-05-05 | — | — | CN | disclosed |
| CN-1131870-C | Novel pyrrole sulfonamide compounds | SUNTORY LTD. (JP) | 2003-12-24 | — | — | CN | disclosed |
| CN-1094126-C | Pyrroloazepine compounds | SUNTORY LTD (JP) | 2002-11-13 | — | — | CN | disclosed |
| CN-1281854-A | Benzothiazine derivative | SUNTORY LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1058492-C | benzothiazine derivatives | SUNTORY LTD (JP) | 2000-11-15 | — | — | CN | disclosed |
| CN-1261366-A | Azothiazine compounds and pyrrolethiazepine compounds having 5-hydroxytryptamine-2-receptor antagonistic and alpha-1-blocking effects | SUNTORY LTD (JP) | 2000-07-26 | — | — | CN | disclosed |
| CN-1260798-A | Has 5-hydroxytryptamine-2 receptor antagonistic effect and alpha1Azothiazine and pyrrolethiazepine compounds with blocking action | SUNTORY LTD (JP) | 2000-07-19 | — | — | CN | disclosed |
| CN-1219173-A | Pyrroloazepine compounds | SUNTORY LTD (JP) | 1999-06-09 | — | — | CN | disclosed |
| CN-1119859-A | benzothiazine derivatives | SUNTORY LTD (JP) | 1996-04-03 | — | — | CN | disclosed |