Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736309 | 0.81 | PYGL (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27625548 | 0.79 | CYP1A2 (0.36) | KCNH2 | |
| SCHEMBL27361620 | 0.79 | CYP11B1 (0.37) | KCNH2HTR2AHTR2CHTR2BPTGS1 | |
| SCHEMBL27736334 | 0.79 | USP2 (0.38) | HTR3APTGS1 | |
| SCHEMBL27756903 | 0.75 | CYP1A2 (0.41) | HDAC1 | |
| SCHEMBL27471678 | 0.73 | RELA (0.50) | CNR2RELAPTGS1HDAC1 | |
| SCHEMBL3212630 | 0.69 | PKM (0.55) | SLC6A2SLC6A4KCNH2HTR3ASLC6A3 | |
| SCHEMBL27568109 | 0.68 | MCOLN3 (0.50) | RELAPTGS1HDAC1 | |
| SCHEMBL3314630 | 0.67 | RELA (0.59) | CNR2RELAPTGS1HDAC1 | |
| SCHEMBL3321000 | 0.67 | RELA (0.59) | CNR2RELAPTGS1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400653-A | 11-beta HSD1 inhibitors | WYETH CORP (US) | 2009-04-01 | — | — | CN | disclosed |
| CN-1164232-A | Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents | ZENECA LTD (GB) | 1997-11-05 | — | — | CN | disclosed |