Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443666 | 0.95 | KDM4E (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8444445 | 0.88 | CHRM2 (0.51) | CA12CA1CA2CA9CHRM2 | |
| Hydrochloric Acid SCHEMBL8440088 | 0.84 | ALDH1A1 (0.41) | KDM4ELMNAGAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8443489 | 0.83 | CYP2D6 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8440812 | 0.83 | LMNA (0.44) | CA12CA9LMNAPOLBL3MBTL1 | |
| SCHEMBL8439554 | 0.82 | KEAP1 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27383917 | 0.71 | PTGS1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8444450 | 0.70 | TNKS (0.40) | CA12CA1CA2CA9CHRM2 | |
| SCHEMBL24526675 | 0.70 | MEN1 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29742535 | 0.70 | MEN1 (0.38) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070173-C | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1158606-A | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |