Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443042 | 0.86 | PPARG (0.49) | TLR7PPARGAGTR2AGTR1 | |
| SCHEMBL9442994 | 0.85 | PPARG (0.50) | TLR7PPARGAGTR2AGTR1 | |
| SCHEMBL27528971 | 0.84 | PPARG (0.55) | PPARGAGTR2AGTR1 | |
| SCHEMBL9442984 | 0.84 | PPARG (0.51) | TLR7PPARGAGTR2AGTR1 | |
| SCHEMBL9443089 | 0.84 | PPARG (0.51) | TLR7PPARGAGTR2AGTR1 | |
| SCHEMBL9443062 | 0.84 | AGTR1 (0.49) | TLR7PPARGAGTR2AGTR1 | |
| SCHEMBL9443092 | 0.84 | PPARG (0.68) | PPARGAGTR2AGTR1 | |
| SCHEMBL9638129 | 0.81 | PPARG (0.57) | PPARGAGTR2AGTR1 | |
| SCHEMBL9847780 | 0.80 | PPARG (0.56) | PPARGAGTR2AGTR1 | |
| SCHEMBL9851425 | 0.80 | AGTR1 (0.56) | PPARGPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051358-A | Condensed imdazole derivatives and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-05-15 | — | — | CN | disclosed |