Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851543 | 0.89 | AGTR1 (0.66) | AGTR1AGTR2PPARGENPP2LMNA | |
| SCHEMBL9443092 | 0.86 | PPARG (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL8958862 | 0.85 | AGTR2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8958752 | 0.84 | CYP19A1 (0.44) | AGTR1AGTR2PPARGENPP2LMNA | |
| SCHEMBL9847780 | 0.83 | PPARG (0.56) | AGTR1AGTR2PPARGCYP19A1 | |
| SCHEMBL27528971 | 0.83 | PPARG (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL9853637 | 0.82 | PPARG (0.74) | AGTR1AGTR2PPARGENPP2LMNA | |
| SCHEMBL9847764 | 0.82 | PPARG (0.55) | AGTR1AGTR2PPARGCYP19A1 | |
| SCHEMBL9442994 | 0.82 | PPARG (0.50) | AGTR1AGTR2PPARG | |
| SCHEMBL9443042 | 0.81 | PPARG (0.49) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |