Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847764 | 0.94 | PPARG (0.55) | PPARGAGTR1AGTR2CYP19A1 | |
| SCHEMBL9443092 | 0.90 | PPARG (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL8560864 | 0.90 | PPARG (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL27528971 | 0.87 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL9638129 | 0.84 | PPARG (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL9851425 | 0.83 | AGTR1 (0.56) | PPARGAGTR1AGTR2CYP19A1 | |
| SCHEMBL8972401 | 0.82 | PPARG (0.70) | PPARGAGTR1AGTR2 | |
| SCHEMBL16487178 | 0.81 | TLR7 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8081261 | 0.81 | AGTR1 (0.48) | PPARGAGTR1AGTR2 | |
| SCHEMBL9442986 | 0.81 | EDNRA (0.54) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |