SCHEMBL27361895

SCHEMBL27361895

CCCC1C=C(C)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.39
ACHE P22303 2/20 0.37
BCHE P06276 1/20 0.37
HTR5A P47898 1/20 0.33
GPR3 P46089 1/20 0.32
HTR2A P28223 1/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27857337 0.90 HTR6 (0.34) HTR6ACHEBCHE
SCHEMBL7939907 0.90 HTR6 (0.41) HTR6ACHEBCHEGPR3HTR2A
SCHEMBL6345275 0.84 ACHE (0.35) HTR6ACHEBCHEGPR3HTR2A
SCHEMBL8861764 0.80 HTR6 (0.47) HTR6GPR3HTR2A
SCHEMBL27461742 0.79 HTR6 (0.48) HTR6ACHEBCHEHTR5AGPR3
SCHEMBL7596435 0.78 HTR6 (0.34) HTR6ACHEBCHEGPR3HTR2A
SCHEMBL7455581 0.78 HTR6 (0.54) HTR6ACHEBCHEHTR5AGPR3
SCHEMBL8083929 0.77 HTR6 (0.33) HTR6ACHEBCHEGPR3HTR2A
SCHEMBL7767462 0.77 HTR6 (0.36) HTR6ACHEBCHEHTR5A
SCHEMBL5702854 0.77 HTR6 (0.36) HTR6ACHEBCHEHTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1196721-C Metallocene compound and its manufacturing method and application in olefins polymerization catalyzer MONTELL TECHNOLOGY COMPANY BV (NL) 2005-04-13 CN disclosed
CN-1355256-A Metallocene compound and its manufacturing method and application in olefins polymerization catalyzer MONTELL TECHNOLOGY COMPANY BV (NL) 2002-06-26 CN disclosed
CN-1075076-C Metallocene compound, preparation method thereof and application thereof in olefin polymerization catalyst MONTELL TECHNOLOGY COMPANY BV (NL) 2001-11-21 CN disclosed
CN-1056149-C Process for preparation of bridged metallocents MONTELL TECHNOLOGY COMPANY BV (NL) 2000-09-06 CN disclosed
CN-1150430-A Metallocene compound, preparation method thereof and application thereof in olefin polymerization catalyst MONTELL TECHNOLOGY COMPANY BV (NL) 1997-05-21 CN disclosed
CN-1143083-A Process for preparation of bridged metallocents MONTELL TECHNOLOGY COMPANY BV (NL) 1997-02-19 CN disclosed
CN-1136548-A Process for preparation of cyclopentadinyl compounds and compounds obtained therefrom MONTELL TECHNOLOGY COMPANY BV (NL) 1996-11-27 CN disclosed