SCHEMBL7596435

SCHEMBL7596435

CC1=CC(C[SiH3])c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.34
GPR3 P46089 1/20 0.33
HTR2A P28223 1/20 0.33
ACHE P22303 2/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD1 P21728 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
ADRA1A P35348 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7939907 0.83 HTR6 (0.41) HTR6GPR3HTR2AACHECHRM2
SCHEMBL6345275 0.82 ACHE (0.35) HTR6GPR3HTR2AACHECHRM2
SCHEMBL8083929 0.78 HTR6 (0.33) HTR6GPR3HTR2AACHECHRM2
SCHEMBL27361895 0.78 HTR6 (0.39) HTR6GPR3HTR2AACHECHRM2
SCHEMBL28735639 0.77 HTR6 (0.33) HTR6GPR3HTR2AACHECHRM2
SCHEMBL8861764 0.74 HTR6 (0.47) HTR6GPR3HTR2ASLC22A2SLC22A3
SCHEMBL4651597 0.72 GPR3 (0.41) GPR3HTR2AACHECHRM2HTR1A
SCHEMBL7937772 0.71 HTR6 (0.42) HTR6HTR2ACHRM2CHRM1SLC6A2
SCHEMBL27857337 0.71 HTR6 (0.34) HTR6ACHEBCHE
Butane SCHEMBL3385732 0.71 ACHE (0.37) GPR3HTR2AACHECHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694563-B1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON MITSUBISHI OIL CORP (JP) 2002-10-30 EP disclosed
US-20020128401-A1 SELF-SUPPORTED HYBRD CATALYSTS FOR THE PRODUCTION OF POLYOLEFINS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-09-12 US disclosed
US-6444605-B1 REACTING A REACTION PRODUCT OF A MAGNESIUM ALKOXIDE OR ARYLOXIDE AND A GROUP IVB METAL ALKOXIDE OR ARYLOXIDE; AND A CYCLIC OR POLYCYCLIC HYDROCARBON; PREPARING POLYOLEFINS WITH BROAD OR BIMODAL MOLECULAR WEIGHT DISTRIBUTION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-09-03 US disclosed
US-6399531-B1 COORDINATION CATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-06-04 US disclosed
US-20020061985-A1 MIXED METAL ALKOXIDE AND CYCLOALKADIENYL CATALYSTS FOR THE PRODUCTION OF POLYOLEFINS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-05-23 US disclosed
WO-2001048037-A1 MIXED METAL ALKOXIDE AND CYCLOALKADIENYL CATALYSTS FOR THE PRODUCTION OF POLYOLEFINS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-07-05 WO disclosed
WO-2001048038-A1 HYBRID ZIEGLER-NATTA AND CYCLOALKADIENYL CATALYSTS FOR THE PRODUCTION OF POLYOLEFINS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-07-05 WO disclosed
US-6111040-A Process for the production of olefinic polymers NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-08-29 US disclosed
US-6077804-A Olefin polymerization catalyst and process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 2000-06-20 US disclosed
EP-0679662-B1 Catalyst component for the polymerization of olefins NIPPON OIL CO LTD (JP) 1999-07-14 EP disclosed
EP-0520811-B1 Catalyst components for polymerization of olefins NIPPON OIL CO LTD (JP) 1996-05-08 EP disclosed
EP-0694563-A1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON OIL COMPANY, LIMITED (JP) 1996-01-31 EP disclosed
EP-0520816-B1 Catalyst components for polymerization of olefins NIPPON OIL CO LTD (JP) 1995-12-13 EP disclosed
EP-0679662-A1 Catalyst component for the polymerization of olefins NIPPON OIL CO. LTD. (JP) 1995-11-02 EP disclosed
US-5451555-A Catalyst components for polymerization of olefins NIPPON OIL CO., LTD. (JP) 1995-09-19 US disclosed
EP-0669346-A1 Solid catalyst components for olefin polymerization and use thereof NIPPON OIL CO. LTD. (JP) 1995-08-30 EP disclosed
US-5387567-A An additional polymerization catalysts consisting of a metal compounds selected from zirconium, titanium, hafnium and organosilane compound; molecular weight controller for broad molecular weight distribution NIPPON OIL CO., LTD. (JP) 1995-02-07 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
EP-0520811-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0520816-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed