Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939907 | 0.82 | HTR6 (0.41) | HTR6GPR3HTR2AACHECHRM2 | |
| SCHEMBL6345275 | 0.80 | ACHE (0.35) | HTR6GPR3HTR2AACHECHRM2 | |
| SCHEMBL7596435 | 0.78 | HTR6 (0.34) | HTR6GPR3HTR2AACHECHRM2 | |
| SCHEMBL28735639 | 0.76 | HTR6 (0.33) | HTR6GPR3HTR2AACHECHRM2 | |
| SCHEMBL8861764 | 0.73 | HTR6 (0.47) | HTR6GPR3HTR2ASLC22A2SLC22A3 | |
| SCHEMBL6444625 | 0.72 | HTR6 (0.42) | HTR6HTR2A | |
| SCHEMBL4651505 | 0.69 | GPR3 (0.35) | GPR3HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7937772 | 0.69 | HTR6 (0.42) | HTR6HTR2ACHRM2CHRM1SLC6A2 | |
| SCHEMBL6520102 | 0.69 | HTR6 (0.40) | HTR6 | |
| SCHEMBL6067259 | 0.69 | HTR6 (0.40) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376154-B2 | Bisindenyl derivative and method for its preparation | TARGOR GMBH (DE) | 2000-09-27 | — | — | EP | disclosed |
| EP-0692486-A2 | Bisindenyl derivative and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| EP-0399348-A2 | Process for preparing ethylenpolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0376154-A2 | Bisindenyl derivative and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | disclosed |