Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 3/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201949 | 0.87 | BMPR1B (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5510757 | 0.85 | BMPR1B (0.48) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL2063005 | 0.83 | BRD4 (0.42) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20353827 | 0.81 | HSD17B10 (0.43) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL17254672 | 0.80 | BMPR1B (0.41) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL15625470 | 0.80 | BMPR1B (0.40) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL14822128 | 0.80 | BMPR1B (0.40) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL16203620 | 0.78 | ALDH1A1 (0.45) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL22152601 | 0.78 | CTSC (0.39) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL12991998 | 0.77 | ATAD2 (0.41) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |