Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 9/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 9/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 9/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 9/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201949 | 0.98 | BMPR1B (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL27361980 | 0.85 | BMPR1B (0.40) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL8126458 | 0.84 | ATAD2 (0.59) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5501201 | 0.84 | ATAD2 (0.43) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5107121 | 0.83 | ATAD2 (0.48) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL5116354 | 0.82 | ATAD2 (0.43) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL2061861 | 0.81 | ATAD2 (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL14528011 | 0.80 | BMPR1B (0.50) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL25315122 | 0.79 | BMPR1B (0.49) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL22667214 | 0.79 | BMPR1B (0.52) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869029-A1 | AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT | Pharmacia & Upjohn Company LLC (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006106426-A1 | AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-12 | — | — | WO | disclosed |