Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362928 | 0.80 | SIRT1 (0.56) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL27362161 | 0.71 | SIRT1 (0.50) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL27362055 | 0.70 | SIRT1 (0.46) | SIRT1FNTAFNTBNSD2KDM4E | |
| SCHEMBL8639079 | 0.69 | POLB (0.57) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL13627449 | 0.69 | SIRT1 (0.49) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL231042 | 0.69 | SIRT1 (0.71) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL315581 | 0.67 | NPC1 (0.59) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL5660360 | 0.66 | POLB (0.53) | SIRT1NSD2KDM4EALDH1A1TDP1 | |
| SCHEMBL5030912 | 0.66 | EDNRA (0.55) | SIRT1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL30407941 | 0.66 | EDNRA (0.52) | KDM4EPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035268-A2 | TAU PATHWAY MODULATORS | QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT (QA) | 2024-02-15 | — | — | WO | disclosed |