Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987608 | 0.77 | CES1 (0.40) | CES1CYP11B2CYP19A1CYP11B1CYP3A4 | |
| SCHEMBL459641 | 0.77 | CES1 (0.40) | CES1CYP11B2CYP19A1CYP11B1CYP3A4 | |
| SCHEMBL21559837 | 0.77 | NPC1 (0.39) | CYP11B2CYP19A1CYP11B1CYP3A4CYP17A1 | |
| SCHEMBL7077942 | 0.77 | TDP1 (0.41) | CYP11B2CYP11B1CYP3A4CYP17A1MAOA | |
| SCHEMBL14036882 | 0.73 | MCL1 (0.38) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8268146 | 0.73 | HTR1A (0.48) | MAOBNPC1MAPTPKMRAB9A | |
| SCHEMBL28295887 | 0.71 | RAB9A (0.45) | CYP11B2CYP3A4CYP17A1SIGMAR1KDM4E | |
| SCHEMBL5119030 | 0.69 | CYP3A4 (0.42) | CES1CYP11B2CYP11B1CYP3A4CYP17A1 | |
| Hydrochloric Acid SCHEMBL8442689 | 0.69 | HTR2B (0.51) | — | |
| SCHEMBL12389562 | 0.69 | XDH (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070173-C | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1158606-A | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |