Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694117 | 0.84 | SMN1; SMN2 (0.37) | ALDH1A1TSHRHSD17B10EP300NPSR1 | |
| SCHEMBL7062249 | 0.80 | ALB (0.35) | ALBEP300POLG | |
| SCHEMBL12883801 | 0.78 | ALB (0.34) | ALBEP300POLG | |
| SCHEMBL12883799 | 0.78 | EP300 (0.39) | ALDH1A1TSHRHSD17B10ALBEP300 | |
| SCHEMBL12883796 | 0.77 | EP300 (0.36) | ALBEP300 | |
| SCHEMBL1223628 | 0.76 | KDM4E (0.41) | ALDH1A1NPSR1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL2470522 | 0.76 | LMNA (0.39) | ALDH1A1TSHRHSD17B10EP300CYP3A4 | |
| SCHEMBL1224511 | 0.76 | ALB (0.34) | ALBEP300 | |
| SCHEMBL5694138 | 0.75 | NPSR1 (0.40) | ALDH1A1TSHRHSD17B10ALBNPSR1 | |
| SCHEMBL27798766 | 0.73 | ALB (0.39) | ALBEP300POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462133-B1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| WO-2011017544-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20030166606-A1 | 5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients | KOLON INDUSTRIES, INC. (KR) | 2003-09-04 | — | — | US | disclosed |
| EP-1311524-A2 | 5'-DEOXY-N-(SUBSTITUTED OXYCARBONYL)-5-FLUOROCYTOSINE AND DERIVATIVES THEREOF, METHOD OF PREPARING SAME, AND ANTICANCER COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENTS | Kolon Industries, Inc. (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002011668-A2 | 5'-DEOXY-N-(SUBSTITUTED OXYCARBONYL)-5-FLUOROCYTOSINE AND DERIVATIVES THEREOF, METHOD OF PREPARING SAME, AND ANTICANCER COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENTS | KOLON INDUSTRIES, INC. (KR) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166606-A1 | 5'-deoxy-n-(substituted oxycarbonyl)-5-fluorocytosine and derivatives thereof, method of preparing same, and anticancer composition comprising same as active ingredients | DUT, RNGTT, MTAP | ALDH1A1 1546/4885TSHR 4751/4885HSD17B10 4025/4885 |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DDT, PFAS, CASP2 | ALDH1A1 173/4885TSHR 3141/4885HSD17B10 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.