Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362937 | 0.85 | MAPT (0.59) | MAPTTP53NPC1RXFP1HPGD | |
| SCHEMBL20538978 | 0.78 | CDC7 (0.50) | MAPTTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2564662 | 0.73 | IDO1 (0.43) | MAPTTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13470766 | 0.73 | ALDH1A1 (0.43) | MAPTTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11327747 | 0.73 | GAA (0.45) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL2624439 | 0.72 | IDO1 (0.41) | MAPTTP53RXFP1KDM4EALDH1A1 | |
| SCHEMBL11160167 | 0.72 | KDM4E (0.55) | MAPTSMN1; SMN2NPC1RAB9ARXFP1 | |
| SCHEMBL221297 | 0.72 | IDO1 (0.42) | MAPTTP53NPC1RAB9ARXFP1 | |
| SCHEMBL13470789 | 0.72 | ALDH1A1 (0.40) | MAPTTP53GAAKDM4EALDH1A1 | |
| SCHEMBL12875755 | 0.72 | MAPT (0.49) | MAPTTP53SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313532-A1 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE | 2025-10-09 | — | — | US | disclosed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313532-A1 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | ADH1A, ALDH1A1, ADH1C | MAPT 1666/4885TP53 2469/4885SMN1; SMN2 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.