Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364669 | 0.86 | NPC1 (0.34) | PKMMAPK1TAAR1NPC1RAB9A | |
| SCHEMBL27362385 | 0.81 | TAAR1 (0.37) | PKMMAPK1TAAR1NPC1RAB9A | |
| SCHEMBL27363422 | 0.79 | KMT2A (0.44) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL27357166 | 0.76 | ATM (0.44) | PKMMAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL27355463 | 0.76 | CTRB1 (0.38) | NPC1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27357170 | 0.76 | HDAC6 (0.38) | PKMMAPK1TAAR1NPC1RAB9A | |
| SCHEMBL27364670 | 0.75 | APP (0.36) | PKMMAPK1TAAR1NPC1RAB9A | |
| SCHEMBL27383640 | 0.75 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL27363485 | 0.71 | GAA (0.32) | GAA | |
| SCHEMBL27379949 | 0.71 | TAAR1 (0.37) | TAAR1ADORA2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | disclosed |