Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455755 | 0.88 | ALOX15 (0.37) | DHFRTYMSOPRM1OPRD1 | |
| SCHEMBL27281269 | 0.82 | MEN1 (0.36) | TYMSMEN1LMNAMAPTKMT2A | |
| SCHEMBL27352373 | 0.76 | DHFR (0.37) | DHFRTYMSAKR1C1OPRM1OPRD1 | |
| SCHEMBL7751772 | 0.73 | DHFR (0.40) | DHFRTYMSAKR1C1OPRM1OPRD1 | |
| SCHEMBL6911184 | 0.73 | DHFR (0.40) | DHFRTYMSAKR1C1OPRM1OPRD1 | |
| SCHEMBL27435440 | 0.67 | CYP3A4 (0.36) | AKR1C1TDP1 | |
| SCHEMBL6914734 | 0.64 | FTO (0.41) | DHFRTYMSAKR1C1OPRM1OPRD1 | |
| SCHEMBL6915372 | 0.64 | BACE1 (0.41) | DHFRTYMSOPRM1OPRD1LMNA | |
| SCHEMBL2832176 | 0.61 | ESR1 (0.65) | DHFRTYMSAKR1C1OPRM1OPRD1 | |
| SCHEMBL29850929 | 0.61 | ESR1 (0.65) | DHFRTYMSAKR1C1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1062001-C | A polycarbonate resin composition | GEN ELECTRIC (US) | 2001-02-14 | — | — | CN | disclosed |
| CN-1141935-A | Thermoplastic resin composition | GEN ELECTRICS CORP (US) | 1997-02-05 | — | — | CN | disclosed |
| CN-1122350-A | A polycarbonate resin composition | GEN ELECTRIC (US) | 1996-05-15 | — | — | CN | disclosed |
| CN-1122349-A | A glass fiber-reinforced polycarbonate resin composition | GEN ELECTRIC (US) | 1996-05-15 | — | — | CN | disclosed |
| CN-1114966-A | Fire-resistent polycarbonate resin composition | GEN ELECTRIC (US) | 1996-01-17 | — | — | CN | disclosed |