Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090930 | 0.86 | TDP1 (0.48) | TDP1LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5210241 | 0.84 | PPARA (0.48) | TDP1LMNAKMT2AALDH1A1TSHR | |
| SCHEMBL11785469 | 0.84 | LMNA (0.47) | TDP1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11778290 | 0.84 | KMT2A (0.45) | TDP1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL5204140 | 0.84 | PPARG (0.46) | TDP1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL10440086 | 0.81 | TDP1 (0.44) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL11988773 | 0.81 | RAB9A (0.47) | TDP1LMNAL3MBTL1PIN1MEN1 | |
| SCHEMBL11863178 | 0.80 | ALDH1A1 (0.45) | TDP1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL9016559 | 0.80 | KMT2A (0.48) | TDP1LMNAPIN1MEN1KMT2A | |
| SCHEMBL11785904 | 0.79 | KMT2A (0.55) | TDP1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037269-B | Substituted pyrazolecarboxylic ketone secretory protease inhibitors and preparation method thereof | 中国人民解放军第二军医大学 | 2018-01-19 | — | — | CN | disclosed |
| CN-1058258-C | 2-[N-substituted amine alkyl]-5-(E)-alkylmethylene or phenylmethylene cyclopentanone derivatives and applications | SHENYANG COLLEGE OF PAHRMACY (CN) | 2000-11-08 | — | — | CN | disclosed |
| CN-1082026-A | The 2-[N-substituted amine alkyl]-5-(E)-alkane methylene radical or Ben Yajiaji cyclopentanone derivatives and relevant using method | SHENYANG COLLEGE OF PHARMACY (CN) | 1994-02-16 | — | — | CN | disclosed |