Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741371 | 0.94 | LMNA (0.52) | LMNAALDH1A1TSHRMAPTCYP2D6 | |
| Cyclopropane SCHEMBL27365076 | 0.83 | TSHR (0.48) | LMNAALDH1A1TSHRMAPTGAA | |
| SCHEMBL26199851 | 0.82 | LMNA (0.46) | LMNAALDH1A1TSHRMAPTCYP2D6 | |
| Cyclohexane SCHEMBL27452018 | 0.78 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTCYP2D6 | |
| Cyclohexane SCHEMBL27646640 | 0.77 | LMNA (0.48) | LMNAALDH1A1TSHRMAPTCYP2D6 | |
| SCHEMBL72471 | 0.77 | LMNA (0.62) | LMNAALDH1A1TSHRMAPTCYP2D6 | |
| SCHEMBL498581 | 0.76 | LMNA (0.52) | LMNAALDH1A1TSHRMAPTCYP2D6 | |
| SCHEMBL6651373 | 0.76 | TSHR (0.55) | LMNAALDH1A1TSHRMAPTGAA | |
| SCHEMBL13502946 | 0.76 | ALDH1A1 (0.40) | LMNAALDH1A1TSHREPHX2 | |
| SCHEMBL17908830 | 0.75 | LMNA (0.52) | LMNAALDH1A1TSHRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200917-C | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| CN-1183090-C | Method for preparation of cyclopropyl acrylic derivative | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| CN-1070833-C | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 2001-09-12 | — | — | CN | disclosed |
| CN-1281846-A | Method for preparation of cyclopropyl acrylic derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1281840-A | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1191856-A | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 1998-09-02 | — | — | CN | disclosed |