SCHEMBL27363958

SCHEMBL27363958

[O-][n+]1cnccc1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308340 0.65
SCHEMBL10534630 0.65
SCHEMBL113414 0.64 LMNA (0.43) KIF11
SCHEMBL20554203 0.61
SCHEMBL7039375 0.61
SCHEMBL3361203 0.60 NOTUM (0.44)
SCHEMBL173641 0.59 KIF11 (0.70) KIF11
Ammonia Solution, Strong SCHEMBL28086851 0.57 KIF11 (0.67) KIF11
Bromide SCHEMBL28026302 0.57 KIF11 (0.67) KIF11
Hydrochloric Acid SCHEMBL7816092 0.57 KIF11 (0.67) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1113487-A Method for preparing pharmaceutically active CNS compounds WELLCOME FOUND (GB) 1995-12-20 CN disclosed
CN-1052306-A Compounds having pharmacological activity on the central nervous system WELLCOME FOUND (GB) 1991-06-19 CN disclosed