Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.52 |
| ▸ | DRD3 | P35462 | 10/20 | 0.52 |
| ▸ | DRD4 | P21917 | 9/20 | 0.52 |
| ▸ | DRD1 | P21728 | 8/20 | 0.52 |
| ▸ | DRD5 | P21918 | 8/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367007 | 0.88 | DRD3 (0.56) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL27365089 | 0.81 | DRD2 (0.51) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30878617 | 0.79 | DRD3 (0.65) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL27365091 | 0.78 | DRD2 (0.54) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL15829965 | 0.75 | DRD2 (0.60) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL25583837 | 0.75 | CCR2 (0.40) | DRD2DRD3DRD4CCR5 | |
| SCHEMBL16785623 | 0.72 | DRD4 (0.53) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL19493951 | 0.72 | SLC18A3 (0.54) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL12320891 | 0.71 | SLC18A3 (0.67) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL27364244 | 0.70 | NOTUM (0.49) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054591-A1 | RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |