Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367007 | 0.93 | DRD3 (0.56) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL27365091 | 0.89 | DRD2 (0.54) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL11619057 | 0.87 | HTR2C (0.61) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL27363346 | 0.82 | CCR2 (0.50) | DRD2DRD4DRD3CCR5TLR9 | |
| SCHEMBL27364225 | 0.82 | KCNH2 (0.47) | DRD2CCR5TRPV6 | |
| SCHEMBL27364231 | 0.81 | DRD2 (0.52) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL15829965 | 0.81 | DRD2 (0.60) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL12320891 | 0.78 | SLC18A3 (0.67) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL3665721 | 0.78 | KCNH2 (0.61) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8590427 | 0.76 | CCR3 (0.55) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054591-A1 | RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |