Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779359 | 0.81 | NCF1 (0.54) | MAPTARMTORMEN1NPC1 | |
| SCHEMBL30779360 | 0.81 | NCF1 (0.54) | MAPTARMTORMEN1NPC1 | |
| SCHEMBL27364556 | 0.79 | IRAK4 (0.47) | ESR1ESR2AAK1 | |
| SCHEMBL16829410 | 0.77 | ESR1 (0.73) | ESR1ESR2MAPTAPPAR | |
| SCHEMBL28992074 | 0.76 | ESR1 (0.77) | ESR1ESR2ARPDGFRBPDGFRA | |
| SCHEMBL16829565 | 0.75 | ESR2 (0.70) | ESR1ESR2MAPTARPDGFRB | |
| SCHEMBL21063869 | 0.74 | MAPT (0.45) | ESR1ESR2MAPTAAK1MEN1 | |
| SCHEMBL27364359 | 0.74 | MAPT (0.47) | MAPTAAK1CYP3A4ROCK1 | |
| SCHEMBL27363696 | 0.73 | MAPT (0.40) | MAPTPRKCAPRKCDPRKD1AAK1 | |
| SCHEMBL3007819 | 0.72 | ESR1 (0.71) | ESR1ESR2ARRAB9AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |