Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779359 | 1.00 | NCF1 (0.54) | NCF1RAB9ANPC1ARCYP3A4 | |
| SCHEMBL27364340 | 0.81 | ESR1 (0.56) | RAB9ANPC1ARCYP3A4MEN1 | |
| SCHEMBL21974426 | 0.77 | NCF1 (0.61) | NCF1RAB9ANPC1ARCYP3A4 | |
| SCHEMBL15683652 | 0.75 | CNR1 (0.56) | NCF1RAB9ANPC1ARCYP3A4 | |
| SCHEMBL2480308 | 0.73 | FDPS (0.53) | MAPTCNR1 | |
| SCHEMBL17449881 | 0.73 | RAB9A (0.62) | NCF1RAB9ANPC1ARCYP3A4 | |
| SCHEMBL30938000 | 0.72 | NPC1 (0.58) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL7914859 | 0.72 | NPC1 (0.58) | RAB9ANPC1ARCYP3A4CYP1A2 | |
| SCHEMBL1298106 | 0.72 | NPC1 (0.61) | NCF1RAB9ANPC1ARCYP3A4 | |
| SCHEMBL5506476 | 0.72 | NCF1 (1.00) | NCF1RAB9ANPC1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581023-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | AbbVie Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |