Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 13/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.43 |
| ▸ | BMP2K | Q9NSY1 | 3/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MYLK2 | Q9H1R3 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.43 |
| ▸ | GAK | O14976 | 2/20 | 0.43 |
| ▸ | CIT | O14578 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.43 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.43 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049511 | 0.86 | ESR2 (0.49) | ESR1ESR2GSK3BDYRK1A | |
| SCHEMBL27364663 | 0.82 | IRAK4 (0.42) | IRAK4AAK1DAPK1MKNK2BMP2K | |
| SCHEMBL27364340 | 0.79 | ESR1 (0.56) | ESR1ESR2AAK1 | |
| SCHEMBL1192656 | 0.78 | ATR (0.50) | IRAK4AAK1JAK2TGFBR1GSK3B | |
| SCHEMBL30953487 | 0.78 | ATR (0.50) | IRAK4AAK1JAK2TGFBR1GSK3B | |
| SCHEMBL27364664 | 0.78 | IRAK4 (0.41) | IRAK4AAK1DAPK1MKNK2BMP2K | |
| SCHEMBL27403784 | 0.76 | IRAK4 (0.54) | IRAK4AAK1DAPK1MKNK2BMP2K | |
| SCHEMBL1289516 | 0.76 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL21672291 | 0.75 | IRAK4 (0.53) | IRAK4AAK1DAPK1MKNK2BMP2K | |
| SCHEMBL16464884 | 0.75 | IRAK4 (0.61) | IRAK4AAK1DAPK1MKNK2BMP2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |